Testosterone Therapy & Heart Health: Why Cardiologist-Guided Care Matters

Jul 02, 2026

For many years, testosterone therapy has raised questions in cardiology. Is it safe for the heart? Could it increase the risk for heart attack, stroke, blood clots, or rhythm problems? And for men with low testosterone, could treatment actually support better cardiovascular health?

The answer is becoming clearer. Testosterone therapy can be safe for many men when it is prescribed for the right reasons and monitored carefully by a physician. For men with heart disease or cardiovascular risk factors, that medical oversight is especially important.

At Upper East Side Cardiology, Dr. Satjit Bhusri takes a heart-focused approach to hormone health, helping patients understand whether testosterone therapy may be appropriate for them.

Testosterone and the heart are connected

Low testosterone is not just a sexual health issue. It is often seen in men with obesity, diabetes, high blood pressure, abnormal cholesterol, metabolic syndrome, and heart failure.

Research has shown that men with lower testosterone levels are more likely to have signs of vascular disease, reduced exercise capacity, and worse heart failure symptoms. In some men, low testosterone may be one more sign that the heart and metabolism are under strain.

That does not mean every man with heart disease needs testosterone. It does mean testosterone deserves to be looked at as part of the bigger cardiovascular picture.

What the newer research shows

A major study called the TRAVERSE trial helped change the conversation around testosterone therapy and heart safety. The study followed more than 5,200 men who received either testosterone therapy or a placebo. These were men with existing cardiovascular disease or significant risk factors.

The study found that testosterone therapy did not increase the combined risk of cardiovascular death, nonfatal heart attack, or nonfatal stroke compared with placebo.

That is reassuring. It suggests that testosterone therapy, when used in properly selected men with documented low testosterone, can be safe from a cardiovascular standpoint.

But testosterone therapy should still be treated as real medicine. The safest approach is to confirm the diagnosis, choose patients carefully, use the right dose, and monitor the heart over time.

Why timing and monitoring matter

Testosterone therapy is not something men should start casually through an online clinic, supplement company, or anti-aging program. A cardiologist can help determine whether treatment makes sense based on the patient’s full health history.

That includes looking at blood pressure, cholesterol, diabetes, weight, sleep apnea, heart rhythm, heart failure history, and any past blood clots. These details matter because testosterone can affect red blood cell production, clotting risk, and rhythm issues in some patients.

Monitoring is also essential. Men on testosterone may need follow-up blood work, blood pressure checks, and screening for symptoms such as palpitations, swelling, shortness of breath, or chest discomfort.

One key number doctors watch is hematocrit, which measures the concentration of red blood cells. Testosterone can raise hematocrit. If it climbs too high, treatment may need to be adjusted or stopped.

Testosterone may help the bigger health picture

In the right patient, testosterone therapy may do more than improve libido or energy. Men with true low testosterone may feel stronger, more active, and more able to exercise. Some may see improvements in body composition and stamina.

Those changes can matter for heart health. Better movement, more muscle, less abdominal fat, and improved metabolic health can all support the cardiovascular system.

Testosterone is not a replacement for proven heart care. It does not take the place of blood pressure treatment, cholesterol management, diabetes care, exercise, weight loss, or heart medications when they are needed. But for selected men, it may be a useful part of a broader plan.

Avoid testosterone shortcuts

Over-the-counter “testosterone boosters” are not the same as prescription testosterone therapy. Many have weak evidence and are not regulated like medications.

Illicit anabolic steroids are far more dangerous. High-dose androgen use can raise blood pressure, worsen cholesterol, enlarge the heart, trigger rhythm problems, and accelerate artery disease.

Prescription testosterone therapy under medical supervision is different. It is measured, monitored, and adjusted based on the patient’s health.

Testosterone therapy can be safe for the heart when it is used for the right patient and managed carefully. For men with cardiovascular disease or risk factors, cardiologist-guided care is the best way to approach it.

Low testosterone and heart health are closely linked. In some men, treating true testosterone deficiency may support better energy, exercise capacity, body composition, and overall cardiovascular wellness.

To learn whether testosterone therapy is safe and appropriate for you, call Upper East Side Cardiology in New York City at 212-752-3464 or request an appointment online.